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Epigenetic Cancer Therapy

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eBook details

  • Title: Epigenetic Cancer Therapy
  • Author : Steven Gray
  • Release Date : January 01, 2015
  • Genre: Medical,Books,Professional & Technical,Science & Nature,Life Sciences,Anatomy & Physiology,
  • Pages : * pages
  • Size : 31462 KB

Description

Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector.

The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver).

The book encompasses both large-scale intergovernmental initiatives as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer.
Concisely summarizes the therapeutic implications of recent, large-scale epigenome studies, including the cancer epigenome atlasDiscusses targeted isoform specific versus pan-specific inhibitors, a rational drug design approach to epigenetics relevant to pharmacoepigenetic clinical applicationsCovers new findings in the interplay between cancer stem cells (CSCs) and drug resistance, demonstrating that epigenetic machinery is a candidate target for the eradication of these CSCs


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